Altoprev (lovastatina de liberación prolongada), Livalo (pitavastatina), Pravacol (pravastatina), Crestor (rosuvastatina) y Zocor (simvastatina). Al igual que otras estatinas, la pravastatina inhibe en forma competitiva a la La coadministración con fibratos (bezafibrato, gemfibrozilo), niacina, eritromicina. fluvastatina mg, lovastatina 40 mg, pravastatina. 40 mg . 3A4: ciclosporina, fibratos (gemfibrozil, bezafibrato, fenofibrato y ciprofibrato).
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Int J Clin Pharmacol Ther. A case report of acute neuromyopathy induced by concomitant use of colchicine and bezafibrate. Pharmacokinetics of pravastatin in heart-transplant patients taking cyclosporin A.
The effect of the newly developed angiotensin receptor II antagonist fimasartan on bezafigrato pharmacokinetics of atorvastatin in relation to OATP1B1 in healthy male volunteers. Cimetidine does not alter atorvastatina pharmacokinetics or LDL-cholesterol reduction. Gemfibrozil-warfarin drug interaction resulting in profound hypoprothrombinemia.
Fenofibrate and warfarin interaction.
Eltrombopag increases plasma rosuvastatin exposure in healthy volunteers. The following Mesh terms were used: Pharmacokinetic drug interaction between gemfibrozil and sitagliptin in healthy Indian male volunteers.
Pharmacokinetics of the oral direct renin inhibitor aliskiren in combination with digoxin, atorvastatin, and ketoconazole in healthy subjects: Drug Metabol Drug Interact.
Itraconazole drastically increases plasma concentrations of lovastatin and lovastatin acid. Similarmente, este efecto se presenta con la colestiramina y la glipizida Baycol withdrawn from market.
Effect of the bile acid sequestrant colesevelam on the pharmacokinetics of pioglitazone, repaglinide, estrogen estradiol, norethindrone, levothyroxine, and glyburide. Effect of colesevelam HCl on single-dose fenofibrate pharmacokinetics. Hypolipidemic agents drug interactions: Molden E, Andersson KS. Effect of rosuvastatin on warfarin pharmacodynamics and pharmacokinetics. Rhabdomyolysis triggered by cytomegalovirus infection in a heart transplant patient on concomitant cyclosporine and atorvastatin therapy.
Thirty-year old man diagnosed with hypercholesterolemia and hypertriglyceridemia treated with bezafibrate and pravastatin, systemic arterial hypertension treated with losartan and a year history of hyperuricemia with gout. Elimination of alfentanil delivered by infusion is not altered by the chronic administration of atorvastatin. A randomized, placebo-controlled trial to evaluate the efficacy, safety, and pharmacodynamic interaction of coadministered amlodipine and atorvastatin in patients with concomitant hypertension and dyslipidemia: Drug interaction between oral atorvastatin and verapamil in healthy subjects: The effects of multiple doses of fenofibrate on the pharmacokinetics of pravastatin and its 3alpha-hydroxy isomeric metabolite.
Rhabdomyolysis caused by a potential sitagliptinovastatin interaction. Not all statins interfere with clopidogrel during antiplatelet prafastatina.
The effect of gemfibrozil on repaglinide pharmacokinetics persists for at least 12 h after the dose: Interaction between a commercially available St. Rhabdomyolysis and acute renal failure induced by combination lovastatin and gemfibrozil therapy.
Pravasttina interaction between troglitazone and atorvastatin. Does cholestyramine interfere with cyclosporine absorption? J Cardiovasc Pharmacol Ther. Atorvastatin does not produce a clinicallysignificant effect on the pharmacokinetics of terfenadine.
Proc West Pharmacol Soc. The effect of gemfibrozil on the pharmacokinetics of rosuvastatin. Concomitant use of simvastatin and amiodarone resulting in severe rhabdomyolysis: Detecting drug interactions from adverse-event reports: Effect of gemfibrozil on the pharmacokinetics of bezafibrsto. Acute rhabdomyolysis caused by combination therapy with atorvastatin and warfarin.
An outpatient drug de-sensitization protocol was initiated, starting with 5 mg, and with gradual dose increases every 4 to 5 days for 59 days until the desired maintenance dose mg was reached. Rhabdomyolysis associated with concurrent use of simvastatina and diltiazem. Pharmacokinetic interaction between oral lovastatin and verapamil in healthy subjects: Lack of effect of gemfibrozil on cyclosporine blood concentrations in kidney-transplanted patients.
Therefore, statins metabolized through CYP3A4 simvastatin, lovastatin and atorvastatin are the ones with the highest number of clinically relevant interactions. Rhabdomyolysis associated with simvastatin-nefazodone therapy. El diltiazem puede causar un aumento bezafibrafo la Cmax en 3,6 veces y el Pravwstatina en 5 veces de la simvastatina y de 3,5 veces el ABC de lovastatina; efecto que no se evidencia en el caso de la pravastatina Effect of gemfibrozil on the pharmacokinetics and pharmacodynamics of glimepiride.
Rapid onset of muscle weakness rhabdomyolysis associated with the combined use of simvastatin and colchicine. Br J Clin Pharmacol. Effect of efavirenz on the pharmacokinetics of simvastatin, atorvastatin, and bezavibrato Pharmacokinetics and pharmacodynamics of fluvastatin in heart transplant recipients taking cyclosporine A. Pharmacokinetic interactions between nelfinavir and 3-hydroxymethylglutaryl coenzyme A reductase bezafibfato atorvastatin and simvastatin.
Accumulation of lovastatin, but not pravastatin, in the blood of cyclosporine-treated kidney graft patients after multiple doses. Acute renal failure with the combined use of rosuvastatin and fenofibrate.